> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SHROOM1 AntibodyBrand |
Leading Biology | Catalog Number |
AMM07812G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SHROOM1 antibody.
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Molecular Weight |
94 kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton.
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
SHROOM1; SHROOM1 antibody is human, mouse and rat reactive. At least three isoforms of SHROOM1 are known to exist; this antibody will detect only the two largest isoforms. SHROOM1 antibody is predicted to not cross-react with other SHROOM family members.
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Isotype |
IgG
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Symbol |
APXL2, KIAA1960
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GeneID |
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UniProt ID |
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Function |
May be involved in the assembly of microtubule arrays during cell elongation.
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Summary |
SHROOM1 Antibody: SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis. It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium. SHROOM1 is also expressed in pulmonary arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmonary arterial hypertension.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Images |
Western blot analysis of SHROOM1 in mouse heart tissue lysate with SHROOM1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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