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MYT1L Antibody

Catalog # Availability Size / Price Inquiry
AMM06535G 0.1 mg / $695

MYT1L Antibody

Brand

Leading Biology

Catalog Number

AMM06535G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MYT1L antibody.

Molecular Weight

130 kDa

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

MYT1L; At least three isoforms are known to exist. This antibody will only recognize the two longest isoforms.

Isotype

IgG

Symbol

KIAA1106

GeneID

UniProt ID

Function

May function as a panneural transcription factor associated with neuronal differentiation. May play a role in the development of neurons and oligodendrogalia in the CNS (By similarity).

Summary

MYT1L Antibody: The myelin transcription factor 1 family, to which the myelin transcription factor 1-like protein (MYT1L) belongs, is expressed primarily in the developing central nervous system and recruits histone deacetylase (HDAC) to regulate neural transcription. Both MYT1L and the related protein MYT1 interact with SIN3B, a protein that mediates transcriptional repression by binding to HDACs, suggesting that the MYT1 family favor the silencing of genes during neural development. Recent studies suggest that polymorphisms of MYT1L may be associated with schizophrenia.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, E

Images

Western blot analysis of MYT1L in mouse brain tissue lysate with MYT1L antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Immunofluorescence of MYT1L in human brain with MYT1L antibody at 20 μg/mL.

Specification

Quantity

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