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SGSM1 Antibody

Catalog # Availability Size / Price Inquiry
AMM07778G 0.1 mg / $695

SGSM1 Antibody

Brand

Leading Biology

Catalog Number

AMM07778G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SGSM1 antibody.

Molecular Weight

126 kDa

Cellular Localization

Antigen Cellular Localization: Golgi apparatus, trans-Golgi network

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

SGSM1; At least four isoforms of SGSM1 are known to exist; SGSM1 antibody will detect all four isoforms.

Isotype

IgG

Symbol

KIAA1941, RUTBC2

GeneID

UniProt ID

Summary

SGSM1 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF, E

Images

Western blot analysis of SGSM1 in human cerebellum tissue lysate with SGSM1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.

Immunofluorescence of SGSM1 in human brain tissue with SGSM1 antibody at 20 μg/mL.

Specification

Quantity

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