> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SGSM1 AntibodyBrand |
Leading Biology | Catalog Number |
AMM07778G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SGSM1 antibody.
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Molecular Weight |
126 kDa
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Cellular Localization |
Antigen Cellular Localization:
Golgi apparatus, trans-Golgi network
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
SGSM1; At least four isoforms of SGSM1 are known to exist; SGSM1 antibody will detect all four isoforms.
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Isotype |
IgG
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Symbol |
KIAA1941, RUTBC2
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GeneID |
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UniProt ID |
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Summary |
SGSM1 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IF, E
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Images |
Western blot analysis of SGSM1 in human cerebellum tissue lysate with SGSM1 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Immunofluorescence of SGSM1 in human brain tissue with SGSM1 antibody at 20 μg/mL. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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