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LRRTM1 Antibody

Catalog # Availability Size / Price Inquiry
APS00036G 0.1 mg / $695

LRRTM1 Antibody

Brand

Leading Biology

Catalog Number

APS00036G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LRRTM1 antibody.

Molecular Weight

58641 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

LRRTM1; LRRTM1 antibody is predicted to not cross-react with other LRRTM family members.

Isotype

IgG

GeneID

UniProt ID

Function

Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level.

Summary

LRRTM1 Antibody: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM1 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of LRRTM1 in mouse brain tissue lysate with LRRTM1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Immunohistochemistry of LRRTM1 in human brain tissue with LRRTM1 antibody at 5 μg/mL.

Immunofluorescence of LRRTM1 in human brain tissue with LRRTM1 antibody at 20 μg/mL.

Specification

Quantity

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