> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ENC-1 AntibodyBrand |
Leading Biology | Catalog Number |
APR11823G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ENC-1 antibody.
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Molecular Weight |
66130 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus matrix. Cytoplasm. Cytoplasm, cytoskeleton
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Host |
Chicken
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Species Reactivity |
Human, Mouse, Rat
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Target |
ENC1;
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Isotype |
IgY
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Symbol |
KLHL37, NRPB, PIG10
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GeneID |
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UniProt ID |
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Function |
Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin- mediated proteasomal degradation mechanism.
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Summary |
ENC-1 Antibody: The ectoderm-neural cortex-1 (ENC-1) protein is an early and highly specific marker of neural induction in vertebrates. It is a kelch family related protein that functions as an actin-binding protein and has been suggested to be involved in the organization of the actin cytoskeleton during neural fate specification and development of the nervous system. ENC-1 has also been shown to be required for adipocyte differentiation when cytoskeletal reorganization and cell shape change from fibroblastic preadipocytes to spherical adipocytes occur.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Images |
Western blot analysis of ENC-1 in mouse kidney muscle tissue lysate with ENC-1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry of ENC-1 in rat kidney tissue with ENC-1 antibody at 5 μg/mL.
Immunofluorescence of ENC-1 in rat kidney tissue with ENC-1 antibody at 20 μg/mL. |
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Specification |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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