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ENC-1 Antibody

Catalog # Availability Size / Price Inquiry
APR11823G 0.1 mg / $695

ENC-1 Antibody

Brand

Leading Biology

Catalog Number

APR11823G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ENC-1 antibody.

Molecular Weight

66130 Da

Cellular Localization

Antigen Cellular Localization: Nucleus matrix. Cytoplasm. Cytoplasm, cytoskeleton

Host

Chicken

Species Reactivity

Human, Mouse, Rat

Target

ENC1;

Isotype

IgY

Symbol

KLHL37, NRPB, PIG10

GeneID

UniProt ID

Function

Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin- mediated proteasomal degradation mechanism.

Summary

ENC-1 Antibody: The ectoderm-neural cortex-1 (ENC-1) protein is an early and highly specific marker of neural induction in vertebrates. It is a kelch family related protein that functions as an actin-binding protein and has been suggested to be involved in the organization of the actin cytoskeleton during neural fate specification and development of the nervous system. ENC-1 has also been shown to be required for adipocyte differentiation when cytoskeletal reorganization and cell shape change from fibroblastic preadipocytes to spherical adipocytes occur.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of ENC-1 in mouse kidney muscle tissue lysate with ENC-1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Immunohistochemistry of ENC-1 in rat kidney tissue with ENC-1 antibody at 5 μg/mL.

Immunofluorescence of ENC-1 in rat kidney tissue with ENC-1 antibody at 20 μg/mL.

Specification

Quantity

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