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SYNGR1 Antibody

Catalog # Availability Size / Price Inquiry
APR13626G 0.1 mg / $695

SYNGR1 Antibody

Brand

Leading Biology

Catalog Number

APR13626G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SYNGR1 antibody.

Molecular Weight

25456 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein Melanosome. Cell junction, synapse. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

SYNGR1;

Isotype

IgG

GeneID

UniProt ID

Function

Involved in the regulation of short-term and long-term synaptic plasticity.

Summary

SYNGR1 Antibody: Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. The gene for SYNGR1is located at chromosome 22q13, a region linked to schizophrenia; however, there is mixed evidence suggesting that mutations in SYNGR1 might be associated with schizophrenia.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of SYNGR1 in rat brain tissue lysate with SYNGR1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.

Immunohistochemistry of SYNGR1 in rat brain tissue with SYNGR1 antibody at 2.5 μg/mL.

Immunofluorescence of SYNGR1 in rat brain tissue with SYNGR1 antibody at 20 μg/mL.

Specification

Quantity

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