> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > LRFN3 AntibodyBrand |
Leading Biology | Catalog Number |
APR12465G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LRFN3 antibody.
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Molecular Weight |
66260 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite. Cell junction, synapse. Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
LRFN3; This antibody is predicted to not cross-react with other members of the LRFN family.
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Isotype |
IgG
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Symbol |
SALM4
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GeneID |
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UniProt ID |
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Function |
Cell adhesion molecule that mediates homophilic cell- cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgrowth in hippocampal neurons (By similarity).
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Summary |
LRFN3 Antibody: LRFN3 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Images |
Western blot analysis of LRFN3 in K562 lysate with LRFN3 antibody at (A) 1 and (B) 2 μg/mL.
Immunohistochemistry of LRFN3 in mouse brain tissue with LRFN3 antibody at 2.5 μg/mL.
Immunofluorescence of LRFN3 in mouse brain tissue with LRFN3 antibody at 20 μg/mL. |
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Specification |
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Quantity |
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