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LRFN3 Antibody

Catalog # Availability Size / Price Inquiry
APR12465G 0.1 mg / $695

LRFN3 Antibody

Brand

Leading Biology

Catalog Number

APR12465G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LRFN3 antibody.

Molecular Weight

66260 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite. Cell junction, synapse. Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

LRFN3; This antibody is predicted to not cross-react with other members of the LRFN family.

Isotype

IgG

Symbol

SALM4

GeneID

UniProt ID

Function

Cell adhesion molecule that mediates homophilic cell- cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgrowth in hippocampal neurons (By similarity).

Summary

LRFN3 Antibody: LRFN3 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of LRFN3 in K562 lysate with LRFN3 antibody at (A) 1 and (B) 2 μg/mL.

Immunohistochemistry of LRFN3 in mouse brain tissue with LRFN3 antibody at 2.5 μg/mL.

Immunofluorescence of LRFN3 in mouse brain tissue with LRFN3 antibody at 20 μg/mL.

Specification

Quantity

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