>
Antigen, Antibodies, ELISA, Western Blot >
Primary Antibody >
Polyclonal Antibodies >
CRMP1 AntibodyBrand |
Leading Biology | Catalog Number |
APR11675G |
Product Type |
Polyclonal Antibodies | Field of Research |
|
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CRMP1 antibody.
|
||
Molecular Weight |
62184 Da
|
||
Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associated with centrosomes and the mitotic spindle during metaphase
|
||
Host |
Rabbit
|
||
Species Reactivity |
Human, Mouse, Rat
|
||
Target |
CRMP1; This antibody is expected to recognize only the longest isoform of CRMP-1.
|
||
Isotype |
IgG
|
||
Symbol |
DPYSL1, ULIP3
|
||
GeneID |
|||
UniProt ID |
|||
Function |
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May participate in cytokinesis.
|
||
Summary |
CRMP1 Antibody: Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity. CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain; later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons.
|
||
Form |
Liquid |
||
Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
Applications |
WB, IHC-P, IF, E
|
||
Images |
Western blot analysis of CRMP1 in rat brain tissue lysate with CRMP1 antibody at (A) 1 and (B) 2 μg/mL. Immunohistochemistry of CRMP-1 in mouse brain tissue with CRMP-1 antibody at 2.5 μg/mL. Immunofluorescence of CRMP1 in mouse brain tissue with CRMP1 antibody at 5 μg/mL. |
||
Specification |
|||
Quantity |
|
Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
1 | Leading Biology | APR03440G | ITGA11 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
2 | Leading Biology | APR04537G | CMIP Antibody (C-term) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
3 | Leading Biology | APR13816G | TRPM5 Antibody | 50 μl | Polyclonal Antibodies |
|
$695.00 | Add Ask | ||
4 | Leading Biology | APR04506G | PCOLCE2 Antibody (Center) | 100 μl | Polyclonal Antibodies |
|
$495.00 | Add Ask | ||
5 | Leading Biology | APR12422G | Human H4 Histamine Receptor (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
$695.00 | Add Ask | ||
6 | Leading Biology | APR26894N | ASPH Polyclonal Antibody | 100ul | Polyclonal Antibodies | Neuroscience>Calcium Signaling |
|
$495.00 | Add Ask |
Complete this form and click send to ask us a question, request a quote or simply say hello.
You have 0 item in your cart
You have 0 item in your inquiry list