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DNAL1 Antibody

Catalog # Availability Size / Price Inquiry
APR15787G 0.1 mg / $695

DNAL1 Antibody

Brand

Leading Biology

Catalog Number

APR15787G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DNAL1 antibody.

Molecular Weight

21533 Da

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

DNAL1;

Isotype

IgG

Symbol

C14orf168

GeneID

UniProt ID

Summary

DNAL1 Antibody: DNAL1 was identified as a potential candidate gene for primary ciliary dyskinesia (PCD), a genetically heterologous disorder characterized by chronic infections of the upper and lower airways that often leads to permanent lung damage, randomization of left/right body symmetry, and reduced fertility. DNAL1 is reported to be expressed solely in tissues carrying motile cilia for flagella and interacts with DNAH5, a protein that when mutated has been shown to result in PCD. It has been suggested that DNAL1 serves a regulatory function for DNAH5 activity in outer dynein arms of sperm flagella, respiratory cilia, and ependymal cilia. DNAL1 has also been recently identified as an HIV dependency factor (HDF), suggesting that DNAL1 may be an important drug target in HIV treatment. At least two isoforms of DNAL1 are known to exist.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, ICC, E

Images

Western blot analysis of DNAL1 in 3T3 cell lysate with DNAL1 antibody at (A) 1 and (B) 2 μg/mL.

Immunocytochemistry of DNAL1 in 3T3 cells with DNAL1 antibody at 2.5 μg/mL.

Specification

Quantity

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