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ELOVL6 Antibody

Catalog # Availability Size / Price Inquiry
APR07678G 0.1 mg / $695

ELOVL6 Antibody

Brand

Leading Biology

Catalog Number

APR07678G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ELOVL6 antibody.

Molecular Weight

Predicted: 29 kDa Observed: 28 kDa

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

ELOVL6;

Isotype

IgG

Symbol

FACE, LCE

GeneID

UniProt ID

Function

Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16:0 acyl-CoAs.

Summary

ELOVL6 Antibody: Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Images

Western blot analysis of ELOVL6 in Human brain tissue lysate with ELOVL6 antibody at (A) 1 and (B) 2 μg/mL.

Immunohistochemistry of ELOVL6 in human brain tissue with ELOVL6 antibody at 5 μg/mL.

Immunofluorescence of ELOVL6 in Human Brain tissue with ELOVL6 antibody at 20 μg/mL.

Specification

Quantity

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