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BAP3 Antibody

Catalog # Availability Size / Price Inquiry
APR15113G 0.1 mg / $695

BAP3 Antibody

Brand

Leading Biology

Catalog Number

APR15113G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BAP3 antibody.

Molecular Weight

131901 Da

Host

Rabbit

Species Reactivity

Human

Target

BAIAP3; BAP3 is known to have two isoforms; this BAP3 antibody will recognize only isoform 2. Lower molecular weight bands may represent cleavage or degradation products.

Isotype

IgG

Symbol

KIAA0734

GeneID

UniProt ID

Summary

BAP3 Antibody: BAP3 was initially identified through interaction in a yeast two-hybrid system with the brain-specific angiogenesis inhibitor 1, a p53-target gene that encodes a seven-span transmembrane protein member of the secretin receptor family. BAP3 is predominantly expressed in the brain and possess high homology with Munc13 and synaptotagmin, suggesting that BAP3 may play a role in regulating neurotransmitter release. Recent experiments have shown that BAP3 is induced in certain tumors such as desmoplastic small round cell tumor. Ectopic expression of BAP3 in tumor cells dramatically enhances growth in low serum conditions and colony formation in soft agar, suggesting that the regulated exocytotic pathway may play a role in cancer cell proliferation.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Images

Western blot analysis of BAP3 in SK-N-SH cell lysate with BAP3 antibody at (A) 1 and (B) 2 μg/mL.

Immunohistochemical staining of human brain tissue using BAP3 antibody at 5 μg/mL.

Specification

Quantity

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