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KLHL1 Antibody

Catalog # Availability Size / Price Inquiry
APR17033G 0.1 mg / $695

KLHL1 Antibody

Brand

Leading Biology

Catalog Number

APR17033G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KLHL1 antibody.

Molecular Weight

82680 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton.

Host

Rabbit

Species Reactivity

Human, Rat

Target

KLHL1;

Isotype

IgG

Symbol

KIAA1490

GeneID

UniProt ID

Function

May play a role in organizing the actin cytoskeleton of the brain cells.

Summary

KLHL1 Antibody: The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins. Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Synonyms

KLHL1 Antibody: MRP2, KIAA1490, Kelch-like protein 1, kelch-like 1 (Drosophila)

Images

Western blot analysis of KLHL1 in human brain cell lysate with KLHL1 antibody at (A) 2 and (B) 4 μg /ml.

Immunohistochemistry of KLHL1 in rat brain tissue with KLHL1 antibody at 10 μg/mL.

Specification

Quantity

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