> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TRPC4 AntibodyBrand |
Leading Biology | Catalog Number |
APR13809G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TRPC4 antibody.
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Molecular Weight |
111575 Da
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
Peptide (C)KEKHAHEEDSSIDYDL, corresponding to amino acid residues 943-958 of mouse TRPC4 (Accession number Q9QUQ5).????Intracellular, C-terminus.
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GeneID |
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UniProt ID |
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Summary |
The Transient Receptor Potential (TRP) superfamily is one of the largest ion channel families and consists of diverse groups of proteins. In mammals about 28 genes encode the TRP ion channel subunits. The mammalian TRP superfamily comprises six subfamilies known as the TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPML (mucolipins), TRPP (polycystin) and the TRPA (ANKTM1) ion channels.1-4The TRPC subfamily consists of seven proteins named TRPC1 to 7 which can be further divided into four subgroups based on their sequence homology and functional similarities:1. TRPC12. TRPC4 and TRPC53. TRPC3, TRPC6, TRPC74. TRPC2.2,5They are highly expressed in the central nervous system and to a lesser extent in peripheral tissues.TRPC4 can form heterotetramers with TRPC1. TRPC4, TRPC1 and TRPC5 can be activated either by calcium store depletion or by GPCR stimulation pathways and are also assumed to form components of store operated channels in some cell types such as salivary gland cells, endothelial cells and vascular smooth muscle cells.6
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Form |
Affinity purified antibody, Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IP
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Dilution |
WB~~1:200-1:2000
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Synonyms |
Short transient receptor potential channel 4, TrpC4, Capacitative calcium entry channel Trp4, Receptor-activated cation channel TRP4, Trpc4, Trrp4
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR26894N | ASPH Polyclonal Antibody | 100ul | Polyclonal Antibodies | Neuroscience>Calcium Signaling |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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