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LMX1B Antibody (CT)

Catalog # Availability Size / Price Inquiry
AMM06323G 100 μg / $545

LMX1B Antibody (CT)

Brand

Leading Biology

Catalog Number

AMM06323G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LMX1B antibody (CT).

Molecular Weight

44917 Da

Cellular Localization

Antigen Cellular Localization: Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}

Host

Rabbit

Species Reactivity

Human, Mouse

Target

LMX1B

Isotype

Rabbit IgG1

GeneID

UniProt ID

Function

Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels.

Summary

The LIM homeobox transcription factor 1B (LMX1B) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning; LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Synonyms

LIM homeobox transcription factor 1 beta, LIM/homeobox protein LMX1B, LIM/homeobox protein 1.2

Images

Specification

Quantity

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