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HTRA3 antibody - middle region

Catalog # Availability Size / Price Inquiry
APR16785G 50 μg / $545

HTRA3 antibody - middle region

Brand

Leading Biology

Catalog Number

APR16785G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HTRA3 antibody - middle region.

Molecular Weight

47kDa

Cellular Localization

Antigen Cellular Localization: Secreted. Note=Secretion increased during decidualization of endometrial stromal cells

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Horse, Guinea Pig, Dog

Symbol

PRSP

GeneID

UniProt ID

Function

Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Synonyms

Serine protease HTRA3, 3.4.21.-, High-temperature requirement factor A3, Pregnancy-related serine protease, HTRA3, PRSP

Images

WB Suggested Anti-HTRA3 Antibody Titration: 1.0 μg/ml Positive Control: Fetal Brain

Specification

Quantity

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