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DGKH antibody - middle region

Catalog # Availability Size / Price Inquiry
APR15730G 50 μg / $545

DGKH antibody - middle region

Brand

Leading Biology

Catalog Number

APR15730G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DGKH antibody - middle region.

Molecular Weight

135kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Cell membrane. Note=Translocated from the cytoplasm to endosomes in response to stress stimuli Isoform 2 is rapidly relocated back to the cytoplasm upon removal of stress stimuli, whereas isoform 1 exhibits sustained endosomal association. Translocates from the cytoplasm to the cell membrane in the presence of active GTP-bound form of HRAS

Host

Rabbit

Species Reactivity

Human, Horse, Dog

GeneID

UniProt ID

Function

Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Synonyms

Diacylglycerol kinase eta, DAG kinase eta, 2.7.1.107, Diglyceride kinase eta, DGK-eta, DGKH

Images

WB Suggested Anti-DGKH Antibody Titration: 0.2-1 μg/ml ELISA Titer: 1:12500 Positive Control: Human Liver

Specification

Quantity

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