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ATP7A antibody - middle region

Catalog # Availability Size / Price Inquiry
APG02167G 50 μg / $545

ATP7A antibody - middle region

Brand

Leading Biology

Catalog Number

APG02167G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATP7A antibody - middle region.

Molecular Weight

163kDa

Cellular Localization

Antigen Cellular Localization: Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Cycles constitutively between the trans- Golgi network (TGN) and the plasma membrane. Predominantly found in the TGN and relocalized to the plasma membrane in response to elevated copper levels Isoform 5: Endoplasmic reticulum.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Pig, Horse, Bovine, Dog

Target

This antibody is will react to isoforms 1-5.

Symbol

MC1, MNK

GeneID

UniProt ID

Function

May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Synonyms

Copper-transporting ATPase 1, 3.6.3.54, Copper pump 1, Menkes disease-associated protein, ATP7A, MC1, MNK

Images

WB Suggested Anti-ATP7A Antibody Titration: .2-1 μg/ml ELISA Titer: 1:3125 Positive Control: HT18 cell lysate ATP7A is supported by BioGPS gene expression data to be expressed in HT18

Lanes: Lane1: 4 ug mouse endothelial firboblast lysate Lane2: 4 ug human HUVEC lysate Primary Antibody Dilution: 1:5 Secondary Antibody: Anti-rabbit HRP Secondary Antibody Dilution: 1:2 Gene Name: ATP7A Submitted by: Anonymous

Specification

Quantity

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