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Doublecortin (DCX) AntibodyBrand |
Leading Biology | Catalog Number |
AMM05839G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Doublecortin (DCX) antibody.
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Molecular Weight |
35, 45 KDa
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Host |
Mouse
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Species Reactivity |
Bovine, Human, Mouse, Rat
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Target |
Full length recombinant human protein expressed in and purified from E. coli.
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Clone |
3 e1
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Isotype |
IgG2A
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GeneID |
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UniProt ID |
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Summary |
Doublecortin, or DCX, is a microtubule associated protein that is expressed almost exclusively in very early neuronal development (Brown et al., 2003), making it an excellent marker for developing neuronal cells. Defects in the DCX gene lead toX-linked lissencephaly which is characterized by a lack of normal folds on the surface of the brain resulting in a smooth cerebral cortex caused by abnormal migration of neurons during development (des Portes et al., 1998; Gleeson et al., 1998).
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Form |
Affinity purified from tissue culture supernatant. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IF, WB
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Dilution |
WB~~ 1:5000
IF~~ 1:1000
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Synonyms |
Neuronal migration protein doublecortin, Doublin, Lissencephalin-X, Lis-X, DCX, DBCN, LISX
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Images |
Western blot of postnatal day 3 rat brain lysate showing specific immunolabeling of the ~35 & 45k doublecortin protein. Immunofluorescence of cultured rat neurons showing strong cytoplasmicstaining of doublecortin (green) in developing neurons and GFAP in red. |
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Specification |
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Quantity |
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