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Ribosomal S6 Kinase 2 Antibody

Catalog # Availability Size / Price Inquiry
AMM07623G 100 μl / $545

Ribosomal S6 Kinase 2 Antibody

Brand

Leading Biology

Catalog Number

AMM07623G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Ribosomal S6 Kinase 2 antibody.

Molecular Weight

90 KDa

Host

Rabbit

Species Reactivity

Human

Target

Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH.

GeneID

UniProt ID

Summary

The p90 ribosomal S6 kinases (RSK)1–4 are downstream membersof the extracellular signal-regulated kinase (ERK)/MAPK cascade.The loss of RSK2 activity inhumans leads to Coffin–Lowrysyndrome, which is characterized by mental retardation andgrowthdeficits (Hanauer and Young, 2002). Recent work suggests that RSK2 exerts a tonicregulation on G-protein coupled signaling (Sheffler et al., 2006).

Form

Prepared from rabbit serum by affinity purification via chromatography onan affinity column made with the C-terminal peptide used as antigen.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB

Dilution

WB~~ 1:1000

Synonyms

Ribosomal protein S6 kinase alpha-2, S6K-alpha-2, 90 kDa ribosomal protein S6 kinase 2, p90-RSK 2, p90RSK2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, MAPKAP kinase 1c, MAPKAPK-1c, Protein-tyrosine kinase Mpk-9, Ribosomal S6 kinase 3, RSK-3, pp90RSK3, Rps6ka2, Mapkapk1c, Rsk3

Images

Western blot of HeLa lysate showing specific immunolabeling of the ~90k RSK2 protein.

Specification

Quantity

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