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Tyrosine Hydroxylase Antibody

Catalog # Availability Size / Price Inquiry
APR10625G 100 μl / $545

Tyrosine Hydroxylase Antibody

Brand

Leading Biology

Catalog Number

APR10625G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Tyrosine Hydroxylase antibody.

Molecular Weight

60 KDa

Host

Sheep

Species Reactivity

Bovine, Human, Mouse, Rat

Target

SDS-denatured, native rat tyrosine hydroxylase purified from pheochromocytoma.

GeneID

UniProt ID

Summary

Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson’s disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999). TH antibodies can also be used to explore basic mechanisms of dopamine and norepinephrine signaling (Witkovsky et al., 2000; Salvatore et al., 2001).

Form

Prepared from sheep serum by affinity purification using a column to which immunogen was coupled. The antibody is predominantly of the IgG1 subclass.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IF

Dilution

WB~~ 1:1000 IF~~ 1:1000

Synonyms

Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase, TH, Th

Images

Western blot of 10 ug of rat caudate lysate showing specific immunolabeling of the ~ 60 k tyrosine hydroxylase proteins.

Immunostaining of rabbit retina showing specific labeling of tyrosine hydroxylase in green.

Specification

Quantity

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