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SLINGSHOT-1L AntibodyBrand |
Leading Biology | Catalog Number |
AMM07883G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SLINGSHOT-1L antibody.
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Molecular Weight |
115.5kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cleavage furrow. Midbody. Note=Also recruited to actin rich membrane protrusions such as lamellipodia, which may allow local control of actin dynamics at sites of cell locomotion Also localized to the cleavage furrow and the midbody during cytokinesis
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Host |
Mouse
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Species Reactivity |
Human
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Clone |
6C11G9
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Isotype |
IgG1
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Symbol |
KIAA1298, SSH1L
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GeneID |
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UniProt ID |
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Function |
Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.
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Form |
Liquid. In PBS containing 0.02% sodium azide. |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC, FC, ICC, E
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Dilution |
E~~1/10000
FC~~1/200 - 1/400
IHC~~1/500 - 1/2000
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Synonyms |
Protein phosphatase Slingshot homolog 1, 3.1.3.16, 3.1.3.48, SSH-like protein 1, SSH-1L, hSSH-1L, SSH1, KIAA1298, SSH1L
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Images |
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); Figure 1: Flow cytometric analysis of Hela cells using SLINGSHOT-1L mouse mAb (green) and negative control (red). Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using SLINGSHOT-1L mouse mAb with DAB staining. |
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Specification |
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Quantity |
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