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SLINGSHOT-1L Antibody

Catalog # Availability Size / Price Inquiry
AMM07883G 100 μl / $545

SLINGSHOT-1L Antibody

Brand

Leading Biology

Catalog Number

AMM07883G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SLINGSHOT-1L antibody.

Molecular Weight

115.5kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cleavage furrow. Midbody. Note=Also recruited to actin rich membrane protrusions such as lamellipodia, which may allow local control of actin dynamics at sites of cell locomotion Also localized to the cleavage furrow and the midbody during cytokinesis

Host

Mouse

Species Reactivity

Human

Clone

6C11G9

Isotype

IgG1

Symbol

KIAA1298, SSH1L

GeneID

UniProt ID

Function

Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, FC, ICC, E

Dilution

E~~1/10000 FC~~1/200 - 1/400 IHC~~1/500 - 1/2000

Synonyms

Protein phosphatase Slingshot homolog 1, 3.1.3.16, 3.1.3.48, SSH-like protein 1, SSH-1L, hSSH-1L, SSH1, KIAA1298, SSH1L

Images

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Figure 1: Flow cytometric analysis of Hela cells using SLINGSHOT-1L mouse mAb (green) and negative control (red).

Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using SLINGSHOT-1L mouse mAb with DAB staining.

Specification

Quantity

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