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TRAP1 / HSP75 Antibody

Catalog # Availability Size / Price Inquiry
APR10539G 50 μl / $495

TRAP1 / HSP75 Antibody

Brand

Leading Biology

Catalog Number

APR10539G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TRAP1 / HSP75 antibody.

Molecular Weight

80110 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion. Mitochondrion inner membrane Mitochondrion matrix

Host

Rabbit

Species Reactivity

Human

Target

Human TRAP1

Isotype

IgG

Symbol

HSP75

GeneID

UniProt ID

Function

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Summary

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (7.5 μg/ml), WB (1:500 - 1:3000),

Synonyms

TRAP1, HSP 75, HSP75, HSP90L, TNFR-associated protein 1, TRAP-1

Images

Anti-TRAP1 / HSP75 antibody IHC staining of human colon.

Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE TRAP1 antibody diluted at 1:3000

Specification

Quantity

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