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AMIGO2 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR11396G 50 μl / $495

AMIGO2 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR11396G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AMIGO2 antibody (C-Terminus).

Molecular Weight

57934 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Nucleus Note=Associated with nucleus as well as plasma membrane Restricted to somata of cerebellar as well as hippocampal neurons (By similarity).

Host

Rabbit

Species Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Function

Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.

Summary

Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, E

Dilution

ELISA (1:80000), IHC-P (10 μg/ml),

Synonyms

AMIGO2, ALI1, Alivin 1, Alivin-1, Alvin 1, AMIGO-2, Amphoterin induced gene 2, Amphoterin-induced protein 2, Transmembrane protein AMIGO2, DEGA

Images

Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)

Immunohistochemical staining of formalin-fixed paraffin-embedded breast carcinoma showing membrane staining with anti-AMIGO2 antibody dilution 1:100.

Specification

Quantity

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