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GABRB3 Antibody (clone S87-25)

Catalog # Availability Size / Price Inquiry
APR11975G 50 μg / $495

GABRB3 Antibody (clone S87-25)

Brand

Leading Biology

Catalog Number

APR11975G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GABRB3 antibody (clone S87-25).

Molecular Weight

54116 Da

Cellular Localization

Antigen Cellular Localization: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein

Host

Mouse

Target

~55 kDa. No cross-reactivity against GABA-A-R-Beta 2 or -Beta 1.

Clone

S87-25

Isotype

IgG1

GeneID

UniProt ID

Function

Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel.

Summary

Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, ICC

Dilution

IHC-P (5 μg/ml),

Synonyms

GABRB3, Cleft palate 1, Cp1, GABAA receptor beta-3 subunit, GABA(A) receptor, beta 3, ECA5, GABA A receptor beta 3

Images

IHC analysis of GABA(A)R Beta 3 in frozen sections of mouse brain extract using GABRB3 antibody.

Anti-GABRB3 antibody IHC staining of human brain, cerebellum, purkinje.

Anti-GABRB3 antibody IHC staining of human kidney.

Specification

Quantity

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