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MFN1 Antibody (N-Terminus)

Catalog # Availability Size / Price Inquiry
APR08440G 50 μg / $495

MFN1 Antibody (N-Terminus)

Brand

Leading Biology

Catalog Number

APR08440G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MFN1 antibody (N-Terminus).

Molecular Weight

84kDa

Cellular Localization

Antigen Cellular Localization: Mitochondrion outer membrane; Multi- pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

MFN1 antibody is human, mouse and rat reactive. MFN1 antibody is predicted to not cross-react with MFN2.

GeneID

UniProt ID

Function

Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.

Summary

Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, ICC, E

Dilution

ICC (5 μg/ml), IHC-P (5 μg/ml), WB (1-2 μg/ml)

Synonyms

Mitofusin-1, 3.6.5.-, Fzo homolog, Transmembrane GTPase MFN1, MFN1

Images

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Western blot analysis of MFN1 in A431 cell lysate with MFN1 antibody at 1 ug/ml.

Immunocytochemistry of MFN1 in A431 cells with MFN1 antibody at 5 ug/mL.

Specification

Quantity

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