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DOK4 Antibody (aa11-60)

Catalog # Availability Size / Price Inquiry
APC00048G 50 μl / $495

DOK4 Antibody (aa11-60)

Brand

Leading Biology

Catalog Number

APC00048G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DOK4 antibody (aa11-60).

Molecular Weight

37kDa

Host

Rabbit

Species Reactivity

Human, Mouse

Target

DOK4 Antibody detects endogenous levels of total DOK4 protein.

GeneID

UniProt ID

Function

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.

Summary

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (1:20000), IHC-P (10 μg/ml), WB (1:500-1:1000)

Synonyms

Docking protein 4, Downstream of tyrosine kinase 4, Insulin receptor substrate 5, IRS-5, IRS5, DOK4

Images

Anti-DOK4 antibody IHC staining of human skeletal muscle.

Western blot of extracts from 293/mouse lung cells, using DOK4 Antibody.

Specification

Quantity

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