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Polyclonal Antibodies >
RAPGEF4 / EPAC2 Antibody (N-Terminus)Brand |
Leading Biology | Catalog Number |
AMM07529G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RAPGEF4 / EPAC2 antibody (N-Terminus).
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Molecular Weight |
116kDa
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Target |
Human RAPGEF4 / EPAC2. At least two isoforms of EPAC2 are known to exist; this antibody will detect only the larger isoform.
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Symbol |
CGEF2, EPAC2
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GeneID |
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UniProt ID |
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Function |
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA- independent exocytosis through interaction with RIMS2 (By similarity).
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Summary |
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA- independent exocytosis through interaction with RIMS2 (By similarity).
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, E
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Dilution |
IF (20 μg/ml), IHC-P (5 μg/ml), WB (1-2 μg/ml)
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Synonyms |
Rap guanine nucleotide exchange factor 4, Exchange factor directly activated by cAMP 2, Exchange protein directly activated by cAMP 2, EPAC 2, cAMP-regulated guanine nucleotide exchange factor II, cAMP-GEFII, RAPGEF4, CGEF2, EPAC2
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Images |
Anti-RAPGEF4 / EPAC2 antibody IHC staining of human testis. Immunofluorescence of EPAC2 in mouse liver tissue with EPAC2 antibody at 20 g/mL. Western blot analysis of EPAC2 in rat liver tissue lysate with EPAC2 antibody at 1 ug/ml in (A)... |
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Specification |
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Quantity |
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