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RAB3GAP1 Antibody (aa538-587)

Catalog # Availability Size / Price Inquiry
APR13046G 50 μl / $495

RAB3GAP1 Antibody (aa538-587)

Brand

Leading Biology

Catalog Number

APR13046G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RAB3GAP1 antibody (aa538-587).

Molecular Weight

111kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Note=In neurons, it is enriched in the synaptic soluble fraction

Host

Rabbit

Species Reactivity

Human

Target

RAB3GAP1 Antibody detects endogenous levels of total RAB3GAP1 protein.

Symbol

KIAA0066, RAB3GAP

GeneID

UniProt ID

Function

Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

Summary

Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (1:40000), IHC-P (5 μg/ml), WB (1:500-1:1000)

Synonyms

Rab3 GTPase-activating protein catalytic subunit, RAB3 GTPase-activating protein 130 kDa subunit, Rab3-GAP p130, Rab3-GAP, RAB3GAP1, KIAA0066, RAB3GAP

Images

Western blot of extracts from 293 cells, using RAB3GAP1 Antibody.

Specification

Quantity

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