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ATG9A Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APG02066G 50 μg / $495

ATG9A Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APG02066G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ATG9A antibody (C-Terminus).

Molecular Weight

94kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Under amino acid starvation or rapamycin treatment, redistributes from a juxtanuclear clustered pool to a dispersed peripheral cytosolic pool. The starvation- induced redistribution depends on ULK1, ATG13, as well as SH3GLB1

Host

Rabbit

Species Reactivity

Human

Target

Human ATG9A.

Symbol

APG9L1

GeneID

UniProt ID

Function

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.

Summary

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF

Dilution

IHC-P (5 μg/ml), WB (1-2 μg/ml),

Synonyms

Autophagy-related protein 9A, APG9-like 1, mATG9, ATG9A, APG9L1

Images

Immunofluorescence of ATG9A in human heart tissue with ATG9A antibody at 20 ug/ml.

Western blot analysis of ATG9A in mouse heart tissue lysate with ATG9A antibody at 1 ug/ml.

Anti-ATG9A antibody IHC of human spleen.

Specification

Quantity

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