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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CDH23 / Cadherin 23 Antibody (aa61-110)

CDH23 / Cadherin 23 Antibody (aa61-110)

Catalog # Availability Size / Price Inquiry
APR11570G 50 μl / $495

CDH23 / Cadherin 23 Antibody (aa61-110)

Brand

Leading Biology

Catalog Number

APR11570G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CDH23 / Cadherin 23 antibody (aa61-110).

Molecular Weight

369kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

CDH23 Antibody detects endogenous levels of total CDH23 protein.

Symbol

KIAA1774, KIAA1812

GeneID

UniProt ID

Function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

Summary

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, IF, E

Dilution

ELISA (1:10000), IF (1:100-1:500), IHC-P (1:100)

Synonyms

Cadherin-23, Otocadherin, CDH23, KIAA1774, KIAA1812

Images

Immunofluorescence of HeLa cells, using CDH23 Antibody.

Anti-CDH23 antibody IHC of human spleen.

Specification

Quantity

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