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FIS1 Antibody (aa11-25)

Catalog # Availability Size / Price Inquiry
AMM04550G 50 μl / $495

FIS1 Antibody (aa11-25)

Brand

Leading Biology

Catalog Number

AMM04550G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FIS1 antibody (aa11-25).

Molecular Weight

17kDa

Cellular Localization

Antigen Cellular Localization: Mitochondrion outer membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Target

A peptide corresponding to amino acids 11-25 of human Fis1 protein was used as the immunogen.

Symbol

TTC11

GeneID

UniProt ID

Function

Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin- related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.

Summary

Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin- related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (5 μg/ml), WB (1:500-1:1000),

Synonyms

Mitochondrial fission 1 protein, FIS1 homolog, hFis1, Tetratricopeptide repeat protein 11, TPR repeat protein 11, FIS1, TTC11

Images

Western blot of Fis1 in A) HeLa and B) NIH 3T3 cell lysate using antibody at 1:1000 dilution.

Specification

Quantity

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