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TRAF1 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APG03013G 50 μg / $495

TRAF1 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APG03013G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TRAF1 antibody (C-Terminus).

Molecular Weight

46kDa

Host

Goat

Species Reactivity

Human, Mouse, Rabbit, Hamster, Bovine

Target

Human TRAF1.

Symbol

EBI6

GeneID

UniProt ID

Function

Adapter molecule that regulates the activation of NF- kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein- ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.

Summary

Adapter molecule that regulates the activation of NF- kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein- ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (1:16000), IHC-P (2.5-3.75 μg/ml), WB (1:16000)

Synonyms

TNF receptor-associated factor 1, Epstein-Barr virus-induced protein 6, TRAF1, EBI6

Images

Anti-TRAF1 antibody IHC of human small intestine.

Specification

Quantity

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