> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TSPO / PBR Antibody (C-Terminus)Brand |
Leading Biology | Catalog Number |
APR10582G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TSPO / PBR antibody (C-Terminus).
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Molecular Weight |
19kDa
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Cellular Localization |
Antigen Cellular Localization:
Mitochondrion membrane; Multi-pass membrane protein
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Host |
Goat
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Species Reactivity |
Human, Mouse
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Target |
Mouse TSPO.
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Symbol |
BZRP, MBR
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GeneID |
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UniProt ID |
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Function |
Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides(PubMed:1847678).
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Summary |
Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides(PubMed:1847678).
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
ELISA (1:16000), IHC-P (3.75 μg/ml), WB (0.5-1 μg/ml)
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Synonyms |
Translocator protein, Mitochondrial benzodiazepine receptor, PKBS, Peripheral-type benzodiazepine receptor, PBR, TSPO, BZRP, MBR
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Images |
TSPO antibody (0.5 ug/ml) staining of Mouse Spleen lysate (35 ug protein/ml in RIPA buffer).
Anti-TSPO / PBR antibody IHC of human adipose.
Anti-TSPO / PBR antibody IHC of human renal tubules. |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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