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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > STXBP1 / MUNC18-1 Antibody (aa279-328)

STXBP1 / MUNC18-1 Antibody (aa279-328)

Catalog # Availability Size / Price Inquiry
APR10319G 50 μl / $495

STXBP1 / MUNC18-1 Antibody (aa279-328)

Brand

Leading Biology

Catalog Number

APR10319G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality STXBP1 / MUNC18-1 antibody (aa279-328).

Molecular Weight

68kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Membrane; Peripheral membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

MUNC-18a Antibody detects endogenous levels of total MUNC-18a protein.

Symbol

UNC18A

GeneID

UniProt ID

Function

May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.

Summary

May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, IF, E

Dilution

ELISA (1:40000), IF (1:100-1:500), IHC-P (10 μg/ml)

Synonyms

Syntaxin-binding protein 1, MUNC18-1, N-Sec1, Protein unc-18 homolog 1, Unc18-1, Protein unc-18 homolog A, Unc-18A, p67, STXBP1, UNC18A

Images

Immunofluorescence of NIH-3T3 cells, using MUNC-18a Antibody.

Anti-STXBP1 antibody IHC of human brain, cortex.

Specification

Quantity

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