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VRL1 / TRPV2 Antibody

Catalog # Availability Size / Price Inquiry
APR13972G 50 μl / $495

VRL1 / TRPV2 Antibody

Brand

Leading Biology

Catalog Number

APR13972G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VRL1 / TRPV2 antibody.

Molecular Weight

86kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Cytoplasm Melanosome. Note=Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Host

Rabbit

Species Reactivity

Human, Mouse

Target

Human and mouse VRL1.

Symbol

VRL

GeneID

UniProt ID

Function

Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.

Summary

Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (10 μg/ml), WB (1:500-1:3000),

Synonyms

Transient receptor potential cation channel subfamily V member 2, TrpV2, Osm-9-like TRP channel 2, OTRPC2, Vanilloid receptor-like protein 1, VRL-1, TRPV2, VRL

Images

Sample(30 g of whole cell lysate). A: A431. B: Raji. 7.5% SDS PAGE. TRPV2 antibody diluted at 1:500.

Sample (30 ug of whole cell lysate).

Anti-TRPV2 antibody IHC of human small intestine, submucosal plexus.

Specification

Quantity

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