• Account
  • Account
    Inquiries
    0

    Inquired items

    0 items total Subtotal:$ 0
  • 会员中心
    Cart

    Added items

    0items total Subtotal:$ 0

All Departments

TRPM2 Antibody (Internal)

Catalog # Availability Size / Price Inquiry
APR10563G 50 μg / $495

TRPM2 Antibody (Internal)

Brand

Leading Biology

Catalog Number

APR10563G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TRPM2 antibody (Internal).

Molecular Weight

171kDa

Cellular Localization

Antigen Cellular Localization: Membrane; Multi-pass membrane protein

Host

Goat

Species Reactivity

Human, Monkey

Target

Human TRPM2.

Symbol

EREG1, KNP3, LTRPC2, TRPC7

GeneID

UniProt ID

Function

Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.

Summary

Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P

Dilution

IHC-P (3.75 μg/ml)

Synonyms

Transient receptor potential cation channel subfamily M member 2, 3.6.1.13, Estrogen-responsive element-associated gene 1 protein, Long transient receptor potential channel 2, LTrpC-2, LTrpC2, Transient receptor potential channel 7, TrpC7, TRPM2, EREG1, KNP3, LTRPC2, TRPC7

Images

Anti-TRPM2 antibody IHC of human brain, cortex.

Anti-TRPM2 antibody IHC of human pancreas.

Specification

Quantity

Related Products

Select Brand Catalog No. Product Name Pack Size Type Field of Research Specification Quantity Price(USD)
1 Leading Biology APR03440G ITGA11 Antibody (N-term) 100 μl Polyclonal Antibodies
$495.00 Add Ask
2 Leading Biology APR04537G CMIP Antibody (C-term) 100 μl Polyclonal Antibodies
$495.00 Add Ask
3 Leading Biology APR13816G TRPM5 Antibody 50 μl Polyclonal Antibodies
$695.00 Add Ask
4 Leading Biology APR04506G PCOLCE2 Antibody (Center) 100 μl Polyclonal Antibodies
$495.00 Add Ask
5 Leading Biology APR26894N ASPH Polyclonal Antibody 100ul Polyclonal Antibodies Neuroscience>Calcium Signaling
$495.00 Add Ask
6 Leading Biology APR05221G Phospho-SMAD2(S118) Antibody 100 μl Polyclonal Antibodies
$495.00 Add Ask
Contact Us

This item has successfully been added to your cart!

You have 0 item in your cart

Your inquiry has successfully been added to your list!

You have 0 item in your inquiry list