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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PRDX1 / Peroxiredoxin 1 Antibody (Internal)

PRDX1 / Peroxiredoxin 1 Antibody (Internal)

Catalog # Availability Size / Price Inquiry
AMR09497G 50 μg / $495

PRDX1 / Peroxiredoxin 1 Antibody (Internal)

Brand

Leading Biology

Catalog Number

AMR09497G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRDX1 / Peroxiredoxin 1 antibody (Internal).

Molecular Weight

22kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV

Host

Goat

Species Reactivity

Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Horse, Bovine, Dog

Target

Human PRDX1 / Peroxiredoxin 1. Reported variants represent identical protein (NP_002565.1, NP_859047.1, NP_859048.1).

Symbol

PAGA, PAGB, TDPX2

GeneID

UniProt ID

Function

Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).

Summary

Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (1:32000), IHC-P (2.5 μg/ml), WB (0.01-0.03 μg/ml)

Synonyms

Peroxiredoxin-1, 1.11.1.15, Natural killer cell-enhancing factor A, NKEF-A, Proliferation-associated gene protein, PAG, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2, PRDX1, PAGA, PAGB, TDPX2

Images

Antibody (0.01 ug/ml) staining of HepG2 lysate (35 ug protein in RIPA buffer).

Anti-PRDX1 / Peroxiredoxin 1 antibody IHC of human placenta.

Anti-PRDX1 / Peroxiredoxin 1 antibody IHC of human thyroid.

Specification

Quantity

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