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CASP1 / Caspase 1 Antibody

Catalog # Availability Size / Price Inquiry
APG02372G 50 μg / $495

CASP1 / Caspase 1 Antibody

Brand

Leading Biology

Catalog Number

APG02372G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CASP1 / Caspase 1 antibody.

Molecular Weight

45kDa

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Rabbit

Species Reactivity

Human

Target

15 amino acid peptide from near the middle of human Caspase-1

Symbol

IL1BC, IL1BCE

GeneID

UniProt ID

Function

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Summary

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, E

Dilution

IHC-P (5 μg/ml), WB (0.5 μg/ml),

Synonyms

Caspase-1, CASP-1, 3.4.22.36, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, Caspase-1 subunit p20, Caspase-1 subunit p10, CASP1, IL1BC, IL1BCE

Images

Immunofluorescence of Caspase-1 in HeLa cells with Caspase-1 antibody at 20 ug/ml.

Anti-Caspase 1 antibody IHC of human heart.

Anti-Caspase 1 antibody IHC of human pancreas.

Specification

Quantity

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