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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SCNN1G / ENaC Gamma Antibody (C-Terminus)

SCNN1G / ENaC Gamma Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
AMR09832G 50 μg / $495

SCNN1G / ENaC Gamma Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

AMR09832G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SCNN1G / ENaC Gamma antibody (C-Terminus).

Molecular Weight

74kDa

Cellular Localization

Antigen Cellular Localization: Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells

Host

Rabbit

Species Reactivity

Human

Target

synthetic peptide corresponding to C-terminal residues of human SCNN1G(Amiloride-sensitive sodium channel gamma-subunit)

GeneID

UniProt ID

Function

Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

Summary

Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

IHC-P (5 μg/ml), WB (1 μg/ml),

Synonyms

Amiloride-sensitive sodium channel subunit gamma, Epithelial Na(+) channel subunit gamma, ENaCG, Gamma-ENaC, Gamma-NaCH, Nonvoltage-gated sodium channel 1 subunit gamma, SCNEG, SCNN1G

Images

Anti-SCNN1G antibody IHC of human kidney.

Specification

Quantity

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