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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PC / Pyruvate Carboxylase Antibody (Internal)

PC / Pyruvate Carboxylase Antibody (Internal)

Catalog # Availability Size / Price Inquiry
APR08960G 50 μg / $495

PC / Pyruvate Carboxylase Antibody (Internal)

Brand

Leading Biology

Catalog Number

APR08960G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PC / Pyruvate Carboxylase antibody (Internal).

Molecular Weight

130kDa

Cellular Localization

Antigen Cellular Localization: Mitochondrion matrix.

Host

Goat

Species Reactivity

Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Horse, Bovine, Dog

Target

Human PC / Pyruvate Carboxylase. All reported variants (NP_000911.2; NP_001035806.1; NP_071504.2) represent identical protein.

GeneID

UniProt ID

Function

Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate.

Summary

Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

ELISA (1:16000), IHC-P (5 μg/ml), WB (0.03-0.1 μg/ml)

Synonyms

Pyruvate carboxylase, mitochondrial, 6.4.1.1, Pyruvic carboxylase, PCB, PC

Images

Antibody (0.03 ug/ml) staining of Mouse Liver lysate (35 ug protein in RIPA buffer).

Specification

Quantity

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