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Polyclonal Antibodies >
PTPRR Antibody (aa249-265)Brand |
Leading Biology | Catalog Number |
APR13027G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PTPRR antibody (aa249-265).
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Molecular Weight |
74kDa
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Cellular Localization |
Antigen Cellular Localization:
Isoform Alpha: Cell membrane; Single-pass type I membrane protein Isoform Gamma: Cytoplasm, perinuclear region. Note=Locates to the perinuclear areas within the cytoplasm
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
Amino acids 249 to 265 of human PTPRR
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Symbol |
ECPTP, PTPRQ
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GeneID |
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UniProt ID |
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Function |
Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).
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Summary |
Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC-P, E
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Dilution |
ELISA (1:1000), IHC-P (10 μg/ml),
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Synonyms |
Receptor-type tyrosine-protein phosphatase R, R-PTP-R, 3.1.3.48, Ch-1PTPase, NC-PTPCOM1, Protein-tyrosine phosphatase PCPTP1, PTPRR, ECPTP, PTPRQ
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Images |
Anti-PTPRR antibody IHC of human skin. |
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Specification |
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Quantity |
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