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PTPRR Antibody (aa249-265)

Catalog # Availability Size / Price Inquiry
APR13027G 50 μg / $495

PTPRR Antibody (aa249-265)

Brand

Leading Biology

Catalog Number

APR13027G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PTPRR antibody (aa249-265).

Molecular Weight

74kDa

Cellular Localization

Antigen Cellular Localization: Isoform Alpha: Cell membrane; Single-pass type I membrane protein Isoform Gamma: Cytoplasm, perinuclear region. Note=Locates to the perinuclear areas within the cytoplasm

Host

Rabbit

Species Reactivity

Human

Target

Amino acids 249 to 265 of human PTPRR

Symbol

ECPTP, PTPRQ

GeneID

UniProt ID

Function

Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).

Summary

Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, E

Dilution

ELISA (1:1000), IHC-P (10 μg/ml),

Synonyms

Receptor-type tyrosine-protein phosphatase R, R-PTP-R, 3.1.3.48, Ch-1PTPase, NC-PTPCOM1, Protein-tyrosine phosphatase PCPTP1, PTPRR, ECPTP, PTPRQ

Images

Anti-PTPRR antibody IHC of human skin.

Specification

Quantity

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