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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > EIF4EBP1 / 4EBP1 Antibody (C-Terminus)

EIF4EBP1 / 4EBP1 Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
APR07666G 50 μg / $495

EIF4EBP1 / 4EBP1 Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

APR07666G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EIF4EBP1 / 4EBP1 antibody (C-Terminus).

Molecular Weight

13kDa

Host

Rabbit

Species Reactivity

Human, Mouse

Target

14 amino acid peptide from near the carboxy-terminus of human 4E-BP1

GeneID

UniProt ID

Function

Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.

Summary

Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, ICC

Dilution

IHC-P (2.5 μg/ml)

Synonyms

Eukaryotic translation initiation factor 4E-binding protein 1, 4E-BP1, eIF4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I, EIF4EBP1

Images

Immunocytochemistry of 4E-BP1 in 3T3 cells with 4E-BP1 antibody at 2 ug/ml.

Specification

Quantity

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