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Polyclonal Antibodies >
DOK1 Antibody (C-Terminus)Brand |
Leading Biology | Catalog Number |
APR07615G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DOK1 antibody (C-Terminus).
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Molecular Weight |
52kDa
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Cellular Localization |
Antigen Cellular Localization:
Isoform 1: Cytoplasm. Nucleus.
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
peptide corresponding to amino acids near the carboxy terminus of human p62dok
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GeneID |
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UniProt ID |
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Function |
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
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Summary |
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, IF, ICC
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Dilution |
IHC-P (5 μg/ml), WB (0.5-1 μg/ml),
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Synonyms |
Docking protein 1, Downstream of tyrosine kinase 1, p62(dok), pp62, DOK1
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Images |
Immunocytochemistry of DOK1 in K562 cells with DOK1 antibody at 2 ug/ml. Immunofluorescence of DOK1 in K562 cells with DOK1 antibody at 10 ug/ml. Western blot of DOK1 in Jurkat (Jur) and THP-1 (THP) cell lysates with DOK1 antibody at 1 ug/ml. |
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Specification |
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Quantity |
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6 | Leading Biology | APR05221G | Phospho-SMAD2(S118) Antibody | 100 μl | Polyclonal Antibodies |
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