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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > AES / Groucho Antibody (C-Terminus)

AES / Groucho Antibody (C-Terminus)

Catalog # Availability Size / Price Inquiry
AMM08744G 50 μg / $495

AES / Groucho Antibody (C-Terminus)

Brand

Leading Biology

Catalog Number

AMM08744G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AES / Groucho antibody (C-Terminus).

Molecular Weight

22kDa

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

16 amino acid peptide from near the carboxy terminus of human AES

Symbol

GRG, GRG5

GeneID

UniProt ID

Function

Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development.

Summary

Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, IF, ICC

Dilution

IHC-P (2.5 μg/ml), WB (1-2 μg/ml),

Synonyms

Amino-terminal enhancer of split, Amino enhancer of split, Gp130-associated protein GAM, Grg-5, Groucho-related protein 5, Protein ESP1, Protein GRG, AES, GRG, GRG5

Images

Immunocytochemistry of AES in HeLa cells with AES antibody at 10 ug/ml.

Immunofluorescence of AES in HeLa cells with AES antibody at 20 ug/ml.

Western blot of AES in 293 cell lysate with AES antibody at (A) 1, (B) 2 and (C) 4 ug/ml.

Specification

Quantity

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