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HCRT / Orexin Antibody

Catalog # Availability Size / Price Inquiry
AMM05308G 50 μl / $495

HCRT / Orexin Antibody

Brand

Leading Biology

Catalog Number

AMM05308G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HCRT / Orexin antibody.

Molecular Weight

13kDa

Cellular Localization

Antigen Cellular Localization: Rough endoplasmic reticulum. Cytoplasmic vesicle. Cell junction, synapse. Note=Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses.

Host

Sheep

Species Reactivity

Human

Target

Specific for human orexin A.

Symbol

OX, PPORX, PPOX

GeneID

UniProt ID

Function

Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.

Summary

Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.

Form

Liquid. In PBS containing 0.02% sodium azide.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, E, IHC-Fr

Dilution

IHC-P (10 μg/ml)

Synonyms

Orexin, Hypocretin, Hcrt, Orexin-A, Hypocretin-1, Hcrt1, Orexin-B, Hypocretin-2, Hcrt2, HCRT, OX, PPORX, PPOX

Images

Anti-HCRT / Orexin antibody IHC of human brain, hypothalamus.

Specification

Quantity

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