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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > GRM6 / MGLUR6 Antibody (N-Terminus)

GRM6 / MGLUR6 Antibody (N-Terminus)

Catalog # Availability Size / Price Inquiry
APR12302G 50 μg / $495

GRM6 / MGLUR6 Antibody (N-Terminus)

Brand

Leading Biology

Catalog Number

APR12302G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GRM6 / MGLUR6 antibody (N-Terminus).

Molecular Weight

95kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=Subject to trafficking from the endoplasmic reticulum to the Golgi apparatus and then to the cell membrane

Host

Rabbit

Species Reactivity

Human, Mouse, Rabbit, Hamster, Monkey, Pig, Bovine, Dog

Target

Human GRM6 / MGLUR6. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GRM7 (73%), GRM4 (67%).

Symbol

GPRC1F, MGLUR6

GeneID

UniProt ID

Function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.

Summary

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P

Dilution

IHC-P (12 μg/ml)

Synonyms

Metabotropic glutamate receptor 6, mGluR6, GRM6, GPRC1F, MGLUR6

Images

Anti-GRM6 / MGLUR6 antibody APR12302G IHC of human eye, retina.

Anti-GRM6 / MGLUR6 antibody IHC of human Ovary, Carcinoma.

Specification

Quantity

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