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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > LPAR2 / EDG4 Antibody (Cytoplasmic Domain)

LPAR2 / EDG4 Antibody (Cytoplasmic Domain)

Catalog # Availability Size / Price Inquiry
APR17210G 50 μg / $495

LPAR2 / EDG4 Antibody (Cytoplasmic Domain)

Brand

Leading Biology

Catalog Number

APR17210G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LPAR2 / EDG4 antibody (Cytoplasmic Domain).

Molecular Weight

39kDa

Cellular Localization

Antigen Cellular Localization: Cell surface. Cell membrane; Multi-pass membrane protein. Note=Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA colocalizes with RALA in the endocytic vesicles

Host

Rabbit

Target

Human LPAR2 / EDG4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Symbol

EDG4, LPA2

GeneID

UniProt ID

Function

Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation.

Summary

Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, ICC

Dilution

IHC-P (10-20 μg/ml)

Synonyms

Lysophosphatidic acid receptor 2, LPA receptor 2, LPA-2, Lysophosphatidic acid receptor Edg-4, LPAR2, EDG4, LPA2

Images

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specification

Quantity

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