> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SMO / Smoothened Antibody (1st Extracellular Domain)Brand |
Leading Biology | Catalog Number |
APR13406G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SMO / Smoothened antibody (1st Extracellular Domain).
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Molecular Weight |
86kDa
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein. Cell projection, cilium
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Host |
Rabbit
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Species Reactivity |
Human
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Target |
Human SMO. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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Symbol |
SMOH
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GeneID |
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UniProt ID |
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Function |
G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
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Summary |
G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
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Form |
Liquid |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
IHC-P
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Dilution |
IHC-P (1:400)
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Synonyms |
Smoothened homolog, SMO, Protein Gx, SMO, SMOH
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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