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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > S1PR5 / EDG8 / S1P5 Antibody (Cytoplasmic Domain)

S1PR5 / EDG8 / S1P5 Antibody (Cytoplasmic Domain)

Catalog # Availability Size / Price Inquiry
APR13188G 50 μg / $495

S1PR5 / EDG8 / S1P5 Antibody (Cytoplasmic Domain)

Brand

Leading Biology

Catalog Number

APR13188G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality S1PR5 / EDG8 / S1P5 antibody (Cytoplasmic Domain).

Molecular Weight

42kDa

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human

Target

Human S1PR5 / EDG8. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DKK3 (61%).

Symbol

EDG8

GeneID

UniProt ID

Function

Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.

Summary

Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins (By similarity). May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells.

Form

Liquid

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P

Dilution

IHC-P (4-7 μg/ml)

Synonyms

Sphingosine 1-phosphate receptor 5, S1P receptor 5, S1P5, Endothelial differentiation G-protein-coupled receptor 8, Sphingosine 1-phosphate receptor Edg-8, S1P receptor Edg-8, S1PR5, EDG8

Images

Anti-S1PR5 / EDG8 antibody APR13188G IHC of human brain, neuron and glia.

Specification

Quantity

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