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GATA1 Antibody (S142)

Catalog # Availability Size / Price Inquiry
APR16077G 0.1 mg / $495

GATA1 Antibody (S142)

Brand

Leading Biology

Catalog Number

APR16077G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GATA1 antibody (S142).

Molecular Weight

42751 Da

Cellular Localization

Antigen Cellular Localization: Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Target

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Isotype

Rabbit IgG

Symbol

ERYF1, GF1

GeneID

UniProt ID

Function

Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.

Summary

This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.

Form

affinity Purified IgG, in PBS, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC, IF

Dilution

WB~~1:500~1:1000 IHC~~1:50~1:100 IF~~1:100~200

Synonyms

Erythroid transcription factor, Eryf1, GATA-binding factor 1, GATA-1, GF-1, NF-E1 DNA-binding protein, GATA1, ERYF1, GF1

Images

Western blot analysis of extracts from K562 cells using GATA1 Antibody (S142) ( APR16077G).

Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using GATA1 Antibody (S142) ( APR16077G).

Immunofluorescence staining of methanol-fixed HeLa cells using GATA1 Antibody (S142) ( APR16077G,Red).

Specification

Quantity

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